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Abstract: The Suzuki-Miyaura(SM) reaction represents a powerful and general method for C – C bond formation in complex molecule synthesis. A simple and highly modular strategy has been reported for making small molecules using the Suzuki- Miyaura coupling iteratively which requires a ligand that can attenuate the reactivity of Boronic acids to withstand various SM conditions and then can be cleaved by mild reagents.  This presentation aims to highlight a unified strategy for the construction of small molecules via the Iterative Suzuki coupling of Boron- protected Boronic acids – MIDA (N- Methyliminodiacidic acid) Boronate esters.

References:

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