KR Prabhu


Phone : +91-80-2293-2787
Home Page :


PhD: IISc, Bangalore, India
(Research Advisor: Prof. S. Chandrasekaran)
Postdoctoral research:
University of Missouri, Columbia, MO, USA

Research Interests

Reagents and Methodologies

  1. Organic Synthesis
  2. Green Chemistry
  3. Asymmetric Catalysis and Synthesis
  4. Organophosphorus Chemistry


At present, his research work is focused on the various aspects of organic synthesis with the major emphasis on the development of new methodologies and their applications in organic synthesis; Development of catalytic working model with different transition metals and organocatalysts with special emphasis on green chemistry and asymmetric synthesis; Development of general strategy for the catalytic homogeneous and heterogeneous reactions in user-friendly methods and their applications in large scale reactions under eco-friendly conditions is another important area of focus; Synthesis of phosphorus based chiral and achiral ligands and their utility in catalytic and biological application.

Representative Publications

  • Regioselective C2-alkenylation of indoles using the N‑benzoyl directinggroup: An efficient Ru-catalyzedcoupling reaction
    V Lanke, KR Prabhu
    Org. Lett. 15, 2013, 2818
  • A Versatile C-H Functionalization of Tetrahydroisoquinolines Catalyzed by Iodine at Aerobic Conditions
    Dhineshkumar, M Lamani, K. Alagiri, KR Prabhu
    Org. Lett. 152013,1092
  • Palladium Catalyzed Coupling of Tosylhydrazones with Aryl and Heteroaryl Halides in the Absence of External Ligands: Synthesis of Substituted Olefins
    DP Ojha, KR Prabhu
    J. Org. Chem. 772010, 11027
    (most read paper in December 2012)
  • NIS Catalyzed Reactions: Amidation of Acetophenones and Oxidative Amination of Propiophenones
    M Lamani, KR Prabhu
    Chem. Eur. J.,18,  2012,14638.
  • CDC Reactions of N-Aryl Tetrahydroisoquinolines Using Catalytic Amounts of DDQ: C H Activation under Aerobic Conditions
    K Alagiri, P Devadig, KR Prabhu
    Chem. Eur. J182012, 5160.
  • Schmidt reaction mediated by TfOH:
    Highly regioselective synthesis of nitriles
    BV Rokade,  KR Prabhu
    J. Org. Chem. 772012, 5364
    (most read paper in May and June 2012)
  • A novel oxidative transformation of alcohols to nitriles: an efficient utility of azide as a nitrogen source
    B Rokade, SK Malekar, KR Prabhu
    Chem. Commun. 442012, 5506.
  • Guanidine catalyzed aerobic reduction:
    A selective aerobic hydrogenation of olefins using aqueous hydrazine
    M Lamani, GS Ravikumara, KR Prabhu
    Chem. Commun. 48, 2012, 6583.
  • Iron catalyzed environmentally benign aerobic reduction of olefins using hydrazine at ambient temperature
    M Lamani, GS Ravikumara, KR Prabhu
    Adv. Synth. Catal. 482012, 6583.
  • An oxidative cross-dehydrogenative-coupling reaction in water using molecular oxygen as the oxidant: vanadium catalyzed indolation of tetrahydroisoquinolines
    K Alagiri, GSR Kumara KR Prabhu
    Chem. Commun47, 2011, 11787.
  • Iodine-catalyzed amination of benzoxazoles:
    A metal-free route to 2-aminobenzoxazoles under mild conditions
    M Lamani, KR Prabhu
    J. Org. Chem. 762011,7938.
  • An efficient oxidation of primary azides catalyzed by copper iodide: A convenient method for the synthesis of nitriles
    M Lamani, KR Prabhu
    Angew. Chem. Int. Ed492010,6622.
  • A concise synthesis of substituted thiourea derivatives in aqueous medium
    MR Maddani and KR Prabhu
    J. Org. Chem752010, 2327

Awards / Honours / Affiliations

Will be updated soon