N. Jayaraman

Professor & Chair

Phone : +91-80-2293-2578 (office); 2293-2406 (lab)
E-mail: jayaraman@iisc.ac.in
Home Page : https://njiisc.in/



M.Sc.: Annamalai University, Chidambaram, 1988
Ph.D.: Indian Institute of Technology, Kanpur (1988 – 1994) (Supervisor: Professor S. Ranganathan)
Postdoctoral Fellow: University of Birmingham, England (1994 – 1997) University of California, Los Angeles, USA (1997 – 1999) (Mentor: Professor Sir J.F. Stoddart)

Research Interests

Major research programs of the group are focused in two areas of organic chemistry and synthesis, namely, carbohydrates and dendrimers.

In carbohydrates, on-going research pertains to:

  • Synthesis of natural and un-natural target sugar molecules;
  • Synthesis and studies of oligosaccharides and glycolipids;
  • Biochemical and biophysical studies of carbohydrate-protein interactions.

In the area of macromolecular dendrimers, the research activities are on:

  • Synthesis of poly(ether imine) and poly(alkyl aryl ether) dendrimers;
  • Organometallic catalysis using multivalent dendritic catalysts;
  • Grafting of dendrons on to one-dimensional polymers and physical studies.

Representative Publications

  • Carbohydrate Chemistry

    • “Facial Selectivities in the Nucleophilic Additions of 2,3-Unsaturated 3-Arylsulfinyl Pyranosides”, Mukherjee, A.; Jayaraman, N. Carbohydr. Res. 2013, 380, 51 – 58.
    • “Glycosidic Bond Hydrolysis in Septanosides: A Comparison of Mono-, Di-, and 2-Chloro-2-Deoxy-Septanosides”, Dey, S.; Jayaraman, N. Carbohydr. Res. 2014, 399, 49 – 56.
    • “Backbone-Modified Amphiphilic Cyclic Di- and Tetrasaccharides”, Daskhan, G. C.; Jayaraman, N. Chem. Commun. 2014, 50, 8554 – 8557.
    • “Synthetic Arabinomannan Glycolipids Impede Mycobacterial Growth, Sliding Motility and Biofilm Structure”, Syal, K.; Maiti, K. G.; Naresh, K.; Avaji, P. G.; Chatterji, D.; Jayaraman, N. Glycoconjugate J. 2016, 33, 763–777.
    • “Synthesis and Structure of Cyclic Trisaccharide with Expanded Glycosidic Linkages”, Maiti, K.; Jayaraman, N. J. Org. Chem. 2016, 81, 4616 – 4622.
    • “Chemical and Enzymatic Approaches to the Synthesis of Cyclic Oligosaccharides”, Maiti, K.; Samanta, G. C.; Daskhan, G. C. ; Jayaraman, N. Carbohydr. Chem. 2017, 42, 165–209.

    Dendrimer Chemistry

    • “Multivalent Dendritic Catalysts in Organometallic Catalysis”, Bagul, R. S.; Jayaraman, N. Inorg. Chim. Acta, 2014, 409, 34–52.
    • “Covalent Assembly-Disassembly of Poly(Ether Imine) Dendritic Macromolecular Monomers and Megamers”, Bagul, R. S.; Jayaraman, N. Polymer, 2014, 55, 5102 – 5110.
    • “Dendritic Bis- and Tetrakis-Iminodiacetic Acid-Boronate Complexes in One-Pot Cross-Coupling Reactions”, Sharma, A.; Kumar, P.; Pal, R.; Jayaraman, N. J. Orgmet. Chem. 2016, 819, 138 – 146.
    • “Multicolor Reversible Thermochromic Properties of Gallic Acid-Cored Polydiacetylenes Appended with Poly(alkyl aryl ether) Dendrons”, Singh, Y.; Jayaraman, N. Macromol. Chem. Phys. 2016, 217, 940 – 950.
    • “In-Plane Modulated Smectic ~A vs Smectic ‘A’ Lamellar Structures in Poly(Ethyl or Propyl Ether Imine) Dendrimers”, Kumar, P.; Rao, D. S.S.; Prasad, S. K.; Jayaraman, N. Polymer, 2016, 86, 98 – 104.
    • “Visual Detection of pH and Biomolecular Interactions at Micromolar Concentrations Aided by a Trivalent Diacetylene-Based Vesicle” Singh, Y.; Jayaraman, N. Macromol. Chem. Phys. 2017, 1700039, pp. 1-11.

Awards / Honours / Affiliations

  • Professor Swaminathan Endowment Lecture, University of Madras, Chennai (2007)
  • Chemical Research Society of India medal (2007)
  • Diamond Jubilee Fellow of the Institute of Chemical Technology, Mumbai (2008-2009)
  • Shanti Swarup Bhatnagar Prize (2009)
  • Rajib Goyal Prize (2011)
  • Fellow of Indian Academy of Sciences, India (2011)